Lee D. Cranmer, M.D., Ph.D.
Assistant Professor, Clinical Medicine

Department of Medicine
Leon Levy Cancer Center 1969J
P.O. Box 245024
Tucson, AZ 85724-5024

Phone: 520-626-0501
E-mail: lcranmer@azcc.arizona.edu

EDUCATION:

University of California, San Diego, 1998 (M.D., Ph.D., biology)

Mayo Graduate School of Medicine, Rochester, Minnesota, 1998-2001 (Residency, Internal Medicine)
University of Arizona, Tucson, Arizona, 2001-2003 (Internship, Medical Oncology)

RESEARCH INTERESTS:

Dr. Cranmer grew up in Southern California. After completing undergraduate studies in Biochemistry at Harvard University, he obtained a Master of Science degree in parasitology from the University of Liverpool/Liverpool School of Topical Medicine in England. Thereafter, he enrolled in the Medical Scientist Training Program at the University of California, San Diego. While there, Dr. Cranmer was supported by a Life and Health Insurance Medical Research Fund scholarship. His graduate research was in the area of viral immunology, with an emphasis on the design of experimental vaccines. After receiving his M.D. and Ph.D in Biology in 1998, Dr. Cranmer completed a residency in internal medicine at the Mayo Clinic in Rochester, Minnesota. He then came to the Arizona Cancer Center at the University of Arizona to complete fellowship training in medical oncology.

It was at the Arizona Cancer Center that Dr. Cranmer began his collaboration with Dr. Evan Hersh in the Melanoma Program. After completion of his training in 2003, Dr. Cranmer remained at the Arizona Cancer Center as a faculty member. He works closely with Dr. Hersh in treating patients with malignant melanoma. Dr. Cranmer is also developing interdisciplinary collaborations in the management of sarcomas, an area in which he has developed a strong interest. Dr. Cranmer also treats patients with general hematologic and oncologic disorders, attends hospital in-patients, and provides outside consultation in clinical drug development, malignant melanoma and sarcoma management.

Dr. Cranmer has strong clinical and basic research programs. He is primary investigator on a number of research protocols in malignant melanoma and is developing protocols for patients with sarcomas. He also has a strong interest in the biology of brain metastasis in melanoma, a significant clinical problem.

Dr. Cranmer collaborates closely with Dr. Katrina Trevor, Ph.D. in basic research and basic science investigations. His two areas of focus are biology of brain metastasis in melanoma and the pathogenesis of synovial sarcoma.

SELECTED PUBLICATIONS:

Ebbinghaus S, Rubin E, Hersh E, Cranmer LD, Bonate PL, Fram RJ, Jekunen A, Weitman S, Hammond LA: A Phase I Study of Dolastatin-15 Analogue Tasidotin (ILX651) Administered Intravenously Daily for 5 Consecutive Days Every 3 Weeks in Patients with Advanced Solid Tumors. Clin Cancer Res 11(21) 7807-7816, 2005.

Cranmer LD, Bandlamuri S, Trevor K, Hersh E: Rodent models of brain metastasis in melanoma. Melanoma Res 5:325-356, 2005.

SPONSORED THROUGH MSRP:

Daniel Combs (MSRP 2007, 2008): “Novel Drug Therapies for the Treatment of Synovial Sarcoma.” and "A pilot study of neurocognitive function in patients treated with adjuvant interferon alpha-2b for high-risk melanoma."

Last updated: 9/22/2008