David G. Johnson, M.D.

Professor, Medicine

Chief, Endocrinology Section

Department of Medicine

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P.O. Box 245021
Tucson AZ 85724-5021

Phone: 626-6376 or 626-7328
E-mail: djohnson@u.arizona.edu

EDUCATION:

Harvard University, 1967 (M.D.)
University of California, San Francisco, 1967-1968 (Internship)

University of California, San Francisco,1968-1969 (Residency)
NIH, 1969-1971 (Research Associate)
University of Washington, 1971-1973 (Senior Fellow in Endocrinology)

HONORS/AWARDS:

RCDA, 1975-1978

MAJOR AREAS OF RESEARCH INTEREST:

1. Diabetes mellitus Regulation of secretion from endocrine pancreas Gastrointestinal hormones Effect of somatostatin analogs on secretion of insulin glucagon, and gastrin

2. Effect of somatostatin analogs on hyperglycemia of diabetic mice and rats

RESEARCH ACTIVITIES:

Hormonal regulation of insulin secretion; effects of glucagon on hepatic glycogenolysis using glucagon analogs synthesized by Dr. V. Hruby; clinical studies treating diabetics and patients with hypercholesterolemia with new medications; functions of the sympathetic nervous system.

STUDENT OPPORTUNITIES THROUGH RESEARCH:

Chance to learn surgical technique on small animals as well as modern laboratory techniques such as radioimmunoassays. Opportunity to do endocrine research from molecular to clinical level.

SPONSORED RESEARCH THROUGH MSRP:

Thomas Toal (MSRP 1983): "Hypoglycemic effects of glucagon antagonists in diabetic rats."

Michael Wenger (MSRP 1985): "The effect of somatostatin analogs on the secretion of growth hormone."
Hylton Joffe (MSRP 1996): "Testing glucagon and somatostatin analogs in rats in vivo and in the isolated perfused rat pancreas."

Jason Levine (MSRP 1996): "The effects of glucagon receptor antagonists and somatostatin analogs in rats in vivo and the isolated perfused rat pancreas."

Last updated: 4/18/2006