Paul A. St. John, Ph.D.
Associate Professor, Cell Biology and Anatomy

Department of of Cell Biology and Anatomy

Life Sciences North 442
P.O. Box 245044
Tucson, AZ 85724-5044
Phone: 626-2553
E-mail: stjohn@u.arizona.edu

EDUCATION:

Harvard College, Cambridge, MA, 1972 (A.B., Biology)
Harvard College, Cambridge, MA, 1980 (Ph.D., Cell Devel. Biol)
Harvard Medical School, 1980-1982 (Postdoc, Pharmacology)

MAJOR AREAS OF RESEARCH INTEREST:

Cell biology and developmental regulation of neurotransmitter receptors
Neurotransmitter receptors on developing vertebrate neurons

STUDENT OPPORTUNITIES THROUGH RESEARCH:

Students will learn how to grow and study neurons, muscle and other cells in culture, how to label selected receptors for neurotransmitters; and how to examine how clinically important in the cells' environment alters these receptors. A primary focus currently is understanding how nicotine and related drugs alter the function of neurons and muscle cells.

SELECTED PUBLICATIONS:

Wu J. Xu L. Kim do Y. Rho JM. St John PA. Lue LF. Coons S. Ellsworth K. Nowak L. Johnson E. Rekate H. Kerrigan JF. Electrophysiological properties of human hypothalamic hamartomas. Annals of Neurology. 58(3):371-82, 2005.

Kumar DV. Nighorn A. St John PA. Role of Nova-1 in regulating alpha2N, a novel glycine receptor splice variant, in developing spinal cord neurons. Journal of Neurobiology. 52(2):156-65, 2002.

Huang Y. Stamer WD. Anthony TL. Kumar DV. St John PA. Regan JW. Expression of alpha(2)-adrenergic receptor subtypes in prenatal rat spinal cord. Brain Research. Developmental Brain Research. 133(2):93-104, 2002.

St John PA. Gordon H. Agonists cause endocytosis of nicotinic acetylcholine receptors on cultured myotubes. Journal of Neurobiology. 49(3):212-23, 2001.

SPONSORED THROUGH MSRP:

Greg Cheeney (MSRP 2007): " Differential activation of caspase-3 in hippocampal glial cells by assembly forms of αβ1-42."

Last updated: 1/29/2008