Baldassarre Stea, M.D., Ph.D.

Professor and Department Head , Radiation Oncology
Clinical Medical Director, Radiation Oncology

Department of Radiation Oncology

Leon Levy Cancer Center 1968
P.O. Box 245081
Tucson AZ 85724-5081
Phone: 626-6723; Fax: 626-3141 
E-mail: bstea@azcc.arizona.edu

EDUCATION:

George Washington University, Washington, D.C., 1983 (M.D.)
University of California, Los Angeles, 1979; Biochemistry (Ph.D.)
George Washington University, 1983-1984; Internal Medicine (Internship)

National Institutes of Health, National Cancer Institute, 1984-1987 (Residency)

HONORS/AWARDS:

-American Cancer Society, Clinical Oncology Career Development Award, 1989
-Travel Grant Award to Paris, France for the 17th International Congress of Radiology, 1989
-American Cancer Society Clinical Oncology Career Development Award (1982-1989); Total 3-year cost: $90,000.
-NIH/NRSA Predoctoral Trainingship, UCLA, 1976-1979

-Alpha Omega Alpha Medical Society, 1982

MAJOR AREA OF RESEARCH INTEREST:

Radiation resistance in brain tumors, spinal transduction inhibition

STUDENT OPPORTUNITIES THROUGH RESEARCH:

Participation in either clinical or basic science research allows a student to develop certain skills that will greatly influence the individual's academic or professional life. These skills allow the student to critically analyze data or research papers, formulate is/her own research plans, conduct research in the most efficient and productive way, and finally, will help familiarize the student with the art of publishing the fruit of their efforts.

SELECTED PUBLICATIONS:

Stea B, Falsey R, Kislin K, Patel J, Glanzberg H, Carey S, Meuillet EJ, Martinez JD: Growth inhibition and radiosensitization of Glioblastoma Multiforme by the EGFR-receptor tyrosine kinase inhibitor ZD1839 (Iressa). Cancer Letters 202,43-51, 2003

Stea B. Suh JH. Boyd AP. Cagnoni PJ. Shaw E. REACH Study Group. Whole-brain radiotherapy with or without efaproxiral for the treatment of brain metastases: Determinants of response and its prognostic value for subsequent survival. International Journal of Radiation Oncology, Biology, Physics. 64(4):1023-30, 2006.

Suh JH. Stea B. Nabid A. Kresl JJ. Fortin A. Mercier JP. Senzer N. Chang EL. Boyd AP. Cagnoni PJ. Shaw E. Phase III study of efaproxiral as an adjunct to whole-brain radiation therapy for brain metastases. Journal of Clinical Oncology. 24(1):106-14, 2006.

Choy H. Nabid A. Stea B. Scott C. Roa W. Kleinberg L. Ayoub J. Smith C. Souhami L. Hamburg S. Spanos W. Kreisman H. Boyd AP. Cagnoni PJ. Curran WJ. Phase II multicenter study of induction chemotherapy followed by concurrent efaproxiral (RSR13) and thoracic radiotherapy for patients with locally advanced non-small-cell lung cancer. Journal of Clinical Oncology. 23(25):5918-28, 2005.

=medical student

SPONSORED RESEARCH THROUGH MSRP:

Nand Bhardwaja (MSRP 1988): "Interaction of CIS-platinum and hyperthermia on nephrotoxicity."
Robert Gin (MSRP 1990): "Determination of optimal protocol in the treatment of glioblastoma multiforme (GBM) with hyperthermia and radiation."

Ruskin Lines (MSRP 1990): "The effect of radiation therapy on the outcome of low-grade gliomas."
Andrew Tang (MSRP 1999): "Potentiation of radiation responses by depression of the VEGF cascade pathway."
Heather Glanzberg (MSRP 2002): "Enhancement of breast cancer treatment by combining radiation therapy with cell signal transduction inhibitors."
Jay Patel (MSRP 2002, 2003): "Co-inhibition f PDGFR and EGFR by receptor-specific tyrosine kinase inhibitors in multiple GBM cell lines." and "PTEN involvement in the mechanism of radiosensitization of U251 GMB cells by DPIEL."
Rachit Kumar (MSRP 2005): "Melanoma cell radiosensitization using Tarceva."
Ron Ellsworth (MSRP 2007, 2008): "Expression of Rad-51 and C-Met in Human Specimens in Gliomas: Mechanisms of Radioresistance and Therapeutic Implications."

HIGH SCHOOL STUDENT RESEARCH PROGRAM:

-R. Daniel Esparza, Salpointe Catholic High School, 1990

-Lyra Helms, Window Rock High School, 2008

Last update: 9/22/2008