Leslie P. Tolbert, Ph.D.

Regents Professor, Neurobiology, Cell Biology & Anatomy, Arizona Research Labs

Gould-Simpson 636
P.O. Box: 210077
Tucson AZ 85721-0077
Phone: 621-6640
E-mail: tolbert@neurobio.arizona.edu

EDUCATION:

Radcliffe College, 1973 (A. B. Applied Mathematics)
Harvard University, Boston, 1978 (Ph.D., Anatomy)

MAJOR AREAS OF RESEARCH INTEREST:

Intercellular interactions in the developing nervous system
Neuron-glia relationships
Functional organization of olfactory systems
Development of the olfactory pathway
Function of olfactory glomeruli

SELECTED PUBLICATIONS:

Tolbert LP. Oland LA. Tucker ES. Gibson NJ. Higgins MR. Lipscomb BW. Bidirectional influences between neurons and glial cells in the developing olfactory system. Progress in Neurobiology. 73(2):73-105, 2004.

Tucker ES. Oland LA. Tolbert LP. In vitro analyses of interactions between olfactory receptor growth cones and glial cells that mediate axon sorting and glomerulus formation. Journal of Comparative Neurology. 472(4):478-95, 2004.

Tucker ES. Tolbert LP. Reciprocal interactions between olfactory receptor axons and olfactory nerve glia cultured from the developing moth Manduca sexta. Developmental Biology. 260(1):9-30, 2003.

Oland LA. Tolbert LP. Key interactions between neurons and glial cells during neural development in insects. Annual Review of Entomology. 48:89-110, 2003.

Lohr C. Tucker E. Oland LA. Tolbert LP. Development of depolarization-induced calcium transients in insect glial cells is dependent on the presence of afferent axons. Journal of Neurobiology. 52(2):85-98, 2002.
Goriely AR. Secomb TW. Tolbert LP. Effect of the glial envelope on extracellular K(+) diffusion in olfactory glomeruli. Journal of Neurophysiology. 87(4):1712-22, 2002.

Higgins MR. Gibson NJ. Eckholdt PA. Nighorn A. Copenhaver PF. Nardi J. Tolbert LP. Different isoforms of fasciclin II are expressed by a subset of developing olfactory receptor neurons and by olfactory-nerve glial cells during formation of glomeruli in the moth Manduca sexta. Developmental Biology. 244(1):134-54, 2002.

Wegerhoff R. Rossler W. Higgins M. Oland LA. Tolbert LP. Fenvalerate treatment affects development of olfactory glomeruli in Manduca sexta. Journal of Comparative Neurology. 430(4):533-41, 2001.

Gibson NJ. Rossler W. Nighorn AJ. Oland LA. Hildebrand JG. Tolbert LP. Neuron-glia communication via nitric oxide is essential in establishing antennal-lobe structure in Manduca sexta. Developmental Biology. 240(2):326-39, 2001.

Dubuque SH. Schachtner J. Nighorn AJ. Menon KP. Zinn K. Tolbert LP. Immunolocalization of synaptotagmin for the study of synapses in the developing antennal lobe of Manduca sexta. Journal of Comparative Neurology. 441(4):277-87, 2001.

SPONSORED RESEARCH THROUGH MSRP:

Peter Sirianni (MSRP): "Induction and stabilization of olfactory glomeruli in the developing insect brain."

Last updated: 5/1/2006